On 1980s, experts training Prader-Willi syndrome and you can Angelman disorder pointed out that both issues had been triggered from the a deletion into the long-arm off chromosome fifteen from inside the the very same area, extending out-of 15q11 so you’re able to 15q13. Students having Prader-Willi disorder keeps really serious mental retardation, bad muscle tone, brief hands and feet, and you may a beneficial voracious appetite (hyperphagia) you to initiate when you look at the young people. As a result, they are often overweight by adolescence. Students that have Angelman disorder, likewise, don’t talk, usually are hyperactive, and you will have seizures and you can bed interruptions. Children which have Prader-Willi problem got passed down its father’s backup away from chromosome fifteen when you find yourself the children having Angelman problem had inherited their mom’s. 繼續閱讀 So it searching for is alarming, just like the two syndromes possess significantly additional phenotypes